Fluid-structure interaction and constitutive modeling for coronary artery bypass grafts

I am working with mechanical testing and MRI data from a longitudinal rabbit study of interposition vein grafts to model how graft tissue evolves after implantation in the arterial environment. Building on the constitutive model discovery methods developed in the vein project, we aim to discover a hyperelastic constitutive model for vein graft tissue across remodeling time points.

The discovered graft model will then be incorporated into cardiovascular fluid-structure interaction simulations of coronary artery bypass grafts. By connecting mechanical testing, data-driven constitutive modeling, and patient-specific simulation workflows, this project aims to study vein graft mechanics, remodeling, and potential contributors to graft failure after bypass surgery.

Advisors and collaborators: Dr. Ruizhi Wang, Prof. Jay Humphrey and Prof. Alison Marsden.